Peripheral Vascular Obstruction in Rheumatoid Arthritis and its Relationship to other Vascular Lesions

Peripheral vascular obstruction in rheumatoid arthritis and its relationship to other vascular lesions.

Gangrene of the terminal portions of the limbs may be due to obstruction in the peripheral vessels, large or small, or it may be associated with cardiac failure as in rheumatic or ischaemic heart disease (Swan and Henderson, 1951), with ball valve thrombi, or with pulmonary disease (Boulet, Serre, Vedel, Vallat, and Mirouze, 1949; Hejtmancik and Bruce, 1953). In a case of mitral stenosis and ga...

Peripheral vascular effect of cortisone in rheumatoid arthritis, scleroderma, and other related conditions.

Many systemic diseases including rheumatoid arthritis are frequently associated with a diminution or redistribution of peripheral blood flow. This may be due to an organic arterial narrowing or occlusion or, alternatively, to a high resting tone in the peripheral vessels which may still be capable under certain conditions of relaxing to a normal calibre. Thus the vasodilatation in the fingers w...

Laminin and vascular proliferation in rheumatoid arthritis.

Laminin is a high molecular weight basement membrane structural glycoprotein. In rheumatoid arthritis and other arthropathies immunoreactive laminin was prominent in synovial blood vessel basement membranes and acted as a marker for them. It codistributed with collagen type IV. Immunohistological reactivity to laminin showed extensive vascular proliferation in rheumatoid arthritis together with...

The Vascular Response in Chronic Rheumatoid Arthritis.

Coronary and peripheral vascular occlusion due to rheumatoid arteritis.

Introduction Vasculitis is a well recognized complication of rheumatoid arthritis tending to occur in individuals with severe seropositive nodular disease. It commonly affects small vessels, particularly the digital arteries where the lesion is usually intimal proliferation without significant arterial wall necrosis. Focal ischaemic micro-infarction often occurs, occasionally leading to localiz...